Last year two first drafts of the human proteome were made available [1,2]. These drafts provide an overview of all proteins detected in different cells and tissues of our body. As proteins are the prime molecular entities responsible for all biological processes these drafts tell...
Prof Albert Heck gave an interesting seminar at the Proteomics forum in Berlin (march 2015). You can view these seminars by following the youtube links below...
Top-down analysis of intact proteins by mass spectrometry provides an ideal platform for comprehensive proteoform characterization, in particular, for the identification and localization of post-translational modifications (PTM) co-occurring on a protein. One of the main bottlenecks in top-down proteomics is insufficient protein sequence coverage caused...
In a recent, open access, article in Molecular Systems Biology researchers from the Biomolecular Mass Spectrometry and Proteomics Group at Utrecht University and The Netherlands Cancer Institute in Amsterdam, report on an integrated analysis of proteomic and phospho‐proteomic data from BRAF inhibitor‐treated melanoma cells and...
An international consortium including Prof. Albert Heck and former lab members Javier Munoz and Marco Benevento, has uncovered the molecular events underlying the biological processes of the creation of stem cells from specialized (e.g. skin) cells, a process called cellular reprogramming. The team also discovered...
The European Proteomics Association (EuPA) has awarded Albert Heck the Proteomics Pioneer Award 2014. This is the most prestigious award of the society. Heck is professor in Biomolecular Mass Spectrometry and Proteomics at Utrecht University and scientific director of the Netherlands Proteomics Centre and the...
Prof Christopher Dobson, who has been awarded the 2014 Dr. H.P. Heineken Prize for Biochemistry and Biophysics (USD 200,000), will be visiting Utrecht University on September 29. Dobson will give a lecture about his research for uncovering the manner in which proteins in the human body...
Please take a moment to listen to the 'De Kennis Van Nu' radio interview (in Dutch) with Prof. Albert Heck, which took place on Tuesday, June 24th. The interview is amongst others about the first draft of the human protein catalogue. Just click here to tune...