Albert Heck holds the chair in Biomolecular Mass Spectrometry and Proteomics. Main research interests are in technology development for proteomics and structural biology. Innovations include new mass analyzers, fragmentation and enrichment techniques, and new sample preparations approaches. Work in proteomics applications focus on stem cell...
Padualaan 8 3584CH Utrecht, Netherlands +31(0)302539761 Bas van Breukelen focuses on the analysis of data originating from proteomic experiments. Bioinformatics tools are developed to identify and quantify proteins presents in those very large datasets. In addition software and algorithms are developed that aid statistical analysis and data visualization. Highlighted publications See...
Richard Scheltema group works on unraveling protein complex topology and dynamics by mass spectrometry. Research focuses on the development of advanced LC/MS-MS platforms and analysis software to provide an in-depth, quantitative view on and spatial information between the proteins & small molecules under investigation. Highlighted publications See my...
Simone Lemeer works on the elucidation of the mechanisms of action of small molecule inhibitors in cancer cells, as well as identification of the intrinsic resistance mechanisms. State of the art, high sensitive, chemical proteomics and phosphoproteomics technology are used to study the dynamic changes...
The Berkers group combines Metabolomics approaches – aimed at studying the small molecule metabolite profile of cells using Mass Spectrometry - with biochemical and chemical biology techniques. By comprehensively profiling metabolic changes in either drug resistant cells or in specific populations of immune cells, we...
Maarten Altelaar develops and implements novel MS based proteomics technologies to study protein regulation and cellular signaling processes. Emphasis lies on neuronal cell differentiation and cancer signaling in acquired drug resistance and immune therapy. High-throughput (phospho)proteomics complemented with top-down MS technologies are used to target...